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dc.contributor.author宇都宮, 正登ja
dc.contributor.author小出, 卓生ja
dc.contributor.author山口, 誓司ja
dc.contributor.author吉岡, 俊昭ja
dc.contributor.author園田, 孝夫ja
dc.contributor.author杉山, 清ja
dc.contributor.alternativeUtsunomiya, Masatoen
dc.contributor.alternativeKoide, Takuoen
dc.contributor.alternativeYamaguchi, Seijien
dc.contributor.alternativeYoshioka, Toshiakien
dc.contributor.alternativeSonoda, Takaoen
dc.contributor.alternativeSugiyama, Kiyoshien
dc.date.accessioned2010-06-01T02:33:54Z-
dc.date.available2010-06-01T02:33:54Z-
dc.date.issued1991-10-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/117344-
dc.description.abstract1)各種漢方成分のなかには, in vitroにて強い結晶成長凝集阻止能を持つものが存在した.2)今回実験に用いた7成分中, 夏枯草および沢瀉に低濃度においても, 強い阻止能を認め, 結石予防薬としての可能性が示唆された.3)各種エキスの阻止能とABPPとの間に相関は認められず, とくに沢瀉の成分中にはGAG以外の阻止物質の存在が示唆されたja
dc.description.abstractThe effects of the compositional drugs of kanpou medicine on the growth and aggregation of calcium oxalate crystals were investigated in vitro. In the seeded crystal system, the inhibitory activities were calculated from the change of the number (Ia), total volume (Ig) and fractional volume (I) of crystals determined by a Coulter Multisizer. Among the tested drugs (Takusha, Akyou, Chorei, Bukuryou, Kasseki, Kinsensou, Kagosou), only Takusha and Kagosou had strong inhibitory activities on the growth and aggregation at the concentration of 5 micrograms/ml and 10 micrograms/ml (Ia greater than 80%, Ig, I greater than 90%). No significant correlation was observed between inhibitory activities and alcian blue precipitable polyanions (ABPP) of each drug. Thus some naturally existing substances composing the kanpou medicine may help prevent the stone formation in clinical use.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.subjectCalcium oxalate crystalen
dc.subjectCoulter counteren
dc.subjectKanpou medicineen
dc.subjectCrystal growth inhibitoren
dc.subjectCrystal aggregation inhibitoren
dc.subject.ndc494.9-
dc.title各種漢方成分による蓚酸カルシウム結晶成長凝集阻止能の検討ja
dc.title.alternativeThe effect of kanpou medicine on the growth and aggregation of calcium oxalate crystals in vitroen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume37-
dc.identifier.issue10-
dc.identifier.spage1097-
dc.identifier.epage1101-
dc.textversionpublisher-
dc.sortkey03-
dc.address大阪大学医学部泌尿器科学教室ja
dc.address大阪大学医学部泌尿器科学教室ja
dc.address大阪大学医学部泌尿器科学教室ja
dc.address大阪大学医学部泌尿器科学教室ja
dc.address大阪大学医学部泌尿器科学教室ja
dc.address静岡県立大学薬学部漢方研究所ja
dc.address.alternativethe Dpartment of Urology, Osaka University Medical Schoolen
dc.address.alternativethe Dpartment of Urology, Osaka University Medical Schoolen
dc.address.alternativethe Dpartment of Urology, Osaka University Medical Schoolen
dc.address.alternativethe Dpartment of Urology, Osaka University Medical Schoolen
dc.address.alternativethe Dpartment of Urology, Osaka University Medical Schoolen
dc.address.alternativethe School of Pharmaceuticalc Sience, University of Shizuokaen
dc.identifier.pmid1755397-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.37 No.10

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