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タイトル: | Cisplatin,Etoposide,Peplomycin三者併用療法にて完全寛解をえた脳転移を有する精巣原発絨毛上皮癌の1例 |
その他のタイトル: | Successful management of choriocarcinoma of the testis with brain metastasis: a case report |
著者: | 兼松, 江巳子 川本, 正吾 山本, 直樹 高橋, 義人 岩田, 英樹 斉藤, 昭弘 栗山, 学 坂, 義人 河田, 幸道 |
著者名の別形: | Kanematsu, Emiko Kawamoto, Shohgo Yamamoto, Naoki Takahashi, Yoshito Iwata, Hideki Saitoh, Akihito Kuriyama, Manabu Ban, Yoshihito Kawada, Yukimichi |
キーワード: | Testicular cancer Choriocarcinoma PEP regimen Brain metastasis |
発行日: | Oct-1992 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 38 |
号: | 10 |
開始ページ: | 1195 |
終了ページ: | 1199 |
抄録: | A 32-year-old Japanese male consulted a clinic complaining of gynecomastia. Right painless scrotal swelling was also detected. Right high orchiectomy was performed, then the surgical specimen was histopathologically confirmed as choriocarcinoma and mature teratoma. The imaging revealed cerebral, pulmonary, retroperitoneal metastases. After 3 courses of combination chemotherapy with cisplatin, etoposide and peplomycin (PEP therapy), the brain metastasis completely disappeared and the serum titer of the tumor markers such as beta-HCG became normal. The regression rates of lung and retroperitoneal metastases were 68% and 27%, respectively. Therefore, retroperitoneal lymph node dissection was performed. After the 5th course of PEP therapy, lung metastases disappeared completely. Until the present, no evidence of disease has persisted. The PEP therapy, which is a salvage therapy for refractory testicular cancer, was performed as first-line chemotherapy in this case. It was an excellent modality against choriocarcinoma, along with the surgical treatment. |
URI: | http://hdl.handle.net/2433/117664 |
PubMed ID: | 1282775 |
出現コレクション: | Vol.38 No.10 |
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