Primary signet ring cell adenocarcinoma of the prostate: a case report and literature review

Abstract

前立腺原発の印環細胞癌の1例を報告する.患者は, 61歳の男性, 頻尿, 排尿時痛を主訴に来院した.経尿道的前立腺生検にて印環細胞癌と判明.放射線療法, ホルモン療法, 抗癌化学療法に抵抗し, 癌性腹膜炎, 全身リンパ節転移にて, 診断後26ヵ月で死亡した.剖検にて, 前立腺原発が確認された, 免疫組織化学的には, CAI9-9およびCEAに陽性, PAPおよびPSAに陰性であった.文献上, 15例目の報告にあたる.

We report a rare case of primary signet ring cell adenocarcinoma of the prostate in a 61-year-old male, who died of systemic lymphatic spread. Autopsy ruled out another primary signet ring cell adenocarcinoma outside the prostate. However, immunohistochemically, the tumor stained negatively for prostate-specific antigen. A review of the literature revealed only 15 case reports, including our case.