原発性陰茎癌17例の臨床的検討

Abstract

1965年1月から1991年12月までの27年間に入院加療した原発性陰茎癌患者17例を対象として臨床的検討を行った。1)年齢は34歳から74歳, 平均63.8歳で, 受診までの期間は平均22.8ヵ月であった。2)主訴は陰茎部腫瘤が最も多く, 包茎を合併した症例は83%であった。形態は腫瘤形成型が多く, 大きさは5cm以下がほとんどであった。3)初診時, 鼠径リンパ節腫脹を認めた症例は8例で, そのうち病理組織学的に転移が証明された症例は5例であった。4)手術療法は15例で, おもに陰茎全または部分切断術が施行されていた。また, 化学療法は9例に, 放射線療法は5例に施行されていた。5)全17例の3年生存率は71%, 5年生存率は56%であった。low stage群とhigh stage群の5年生存率はそれぞれ75%, 0%で両者に有意差を認めた

A clinical evaluation of 17 patients with penile cancer treated in our hospital from 1965 to 1991 were surveyed. They were between 34 and 74 years old with a mean age of 63.8 years. The average interval between the onset and the first visit was 22.8 months. Fourteen patients (83%) complained of the manifestation of a tumor and 14 patients (83%) were phimotic. The stage classified according to Jackson was Stage I for 6, Stage II for 6, Stage III for 4 and Stage IV for 1 patient. At the first visit, the inguinal lymph nodes were palpated in 8 patients and metastasis was confirmed in 5 (63%) of them. Surgical treatment was given to 15 patients (88%) (radical or partial penectomy was performed in most cases). Chemotherapy was given to 9 patients (60%) (main chemotherapeutic agent was bleomycin) and irradiation to 5 patients (30%). The overall 3-year survival rate was 71%, and 5-year survival rate was 56%. The 5-year survival rate in the low stage group (Stage I, II) was 75%, while that in the high stage group (Stage III, IV) was 0%, showing a significant difference.