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DCフィールド | 値 | 言語 |
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dc.contributor.author | 筧, 善行 | ja |
dc.contributor.author | 橋村, 孝幸 | ja |
dc.contributor.author | 吉田, 修 | ja |
dc.contributor.author | 清川, 岳彦 | ja |
dc.contributor.author | 兼松, 明弘 | ja |
dc.contributor.alternative | Kakehi, Yoshiyuki | en |
dc.contributor.alternative | Hashimura, Takayuki | en |
dc.contributor.alternative | Yoshida, Osamu | en |
dc.contributor.alternative | Segawa, Takehiko | en |
dc.contributor.alternative | Kanematsu, Akihiro | en |
dc.date.accessioned | 2010-06-01T04:12:56Z | - |
dc.date.available | 2010-06-01T04:12:56Z | - |
dc.date.issued | 1993-12 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/117996 | - |
dc.description.abstract | A bisbenzylisoquinoline alkaloid, cepharanthine, significantly enhanced vinblastine, adriamycin and etoposide sensitivities in P-glycoprotein positive renal cancer cells. However, it did not show any enhancing effect on cisplatin sensitivity. Four patients with metastatic renal cell carcinomas were treated with intraarterial chemotherapy using vinblastine and/or adriamycin in combination with cepharanthine for their metastatic lesions (3 bone and 1 contralateral kidney metastases). A partial response was observed in 1 patient with femoral bone metastasis and a minor response in 1 patient with lumbar bone metastasis, although they were also treated with interferons. No adverse effects associated with cepharanthine were seen except in one patient complaining of redness and burning sense of the skin probably due to its vaso-dilatation effect. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | MDR | en |
dc.subject | Renal cell carcinoma | en |
dc.subject | Bisbenzylisoquinoline | en |
dc.subject.ndc | 494.9 | - |
dc.title | Bisbenzylisoquinolineによる腎癌の多剤耐性の克服 | ja |
dc.title.alternative | Circumvention of the multidrug-resistance in renal cancer by bisbenzylisoquinoline | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 39 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 1227 | - |
dc.identifier.epage | 1232 | - |
dc.textversion | publisher | - |
dc.sortkey | 23 | - |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address | 国立姫路病院泌尿器科 | ja |
dc.address | 国立姫路病院泌尿器科 | ja |
dc.address.alternative | the Department of Urology, Kyoto University Faculty of Medicine | en |
dc.address.alternative | the Department of Urology, Kyoto University Faculty of Medicine | en |
dc.address.alternative | the Department of Urology, Kyoto University Faculty of Medicine | en |
dc.address.alternative | the Department of Urology, National Himeji Hospital | en |
dc.address.alternative | the Department of Urology, National Himeji Hospital | en |
dc.identifier.pmid | 8285174 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.39 No.12 |
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