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Title: 膀胱癌の臨床的観察 : 各年齢別の臨床像の特徴について
Other Titles: Clinical observations on bladder cancer--difference in clinical features with age
Authors: 野口, 純男  KAKEN_name
窪田, 吉信  KAKEN_name
執印, 太郎  KAKEN_name
増田, 光伸  KAKEN_name
矢尾, 正祐  KAKEN_name
三浦, 猛  KAKEN_name
森山, 正敏  KAKEN_name
桜本, 敏夫  KAKEN_name
石橋, 克夫  KAKEN_name
三崎, 博司  KAKEN_name
千葉, 喜美男  KAKEN_name
宮本, 浩  KAKEN_name
金子, 茂樹  KAKEN_name
諏訪, 裕  KAKEN_name
中井川, 昇  KAKEN_name
穂坂, 正彦  KAKEN_name
Author's alias: Noguchi, Sumio
Kubota, Yoshinobu
Shuin, Taro
Masuda, Mitsunobu
Yao, Masahiro
Miura, Takeshi
Moriyama, Masatoshi
Sakuramoto, Toshio
Ishibashi, Yoshio
Misaki, Hiroshi
Chiba, Kimio
Miyamoto, Hiroshi
Kaneko, Shigeki
Suwa, Yutaka
Nakaigawa, Noboru
Hosaka, Masahiko
Keywords: Bladder cancer
Issue Date: Dec-1993
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 39
Issue: 12
Start page: 1131
End page: 1138
Abstract: 原発性膀胱癌患者394例を対象として,年齢群別に,各群の臨床像を比較検討した。1)主訴は血尿が最も多く,全群間で差はなかったが,若年者では主訴発現から受診までの期間が長かった。2)高齢者群に多発性で大きな腫瘍が発生する傾向が認められた。3)高齢者群にhigh gradeでhigh stageの腫瘍の発生する頻度が高かった。4)TUR-BT後の5年非再発率は高齢者とくに80歳以上で有意に低かった。5)5年生存率は高齢者で有意に低かったが,膀胱全摘除術後の5年生存率には有意差は認められなかった
Three hundred and ninety-four patients with transitional cell carcinoma of the bladder who initially visited Yokohama City University Hospital were reviewed according to age group. The patients were divided into four groups, group A (less than 49 years old), group B (from 50 to 64 years old), group C (from 65 to 79 years old) and group D (more than 80 years old). The clinical characteristics as follows were obtained by statistical analysis compared with these four groups. No statistical significance was obtained about frequency of macroscopic hematuria as chief complaint. However, the younger age groups (A and B) tended to visit hospital later after the first symptom of hematuria. The older age groups (C and D) had multiple and large tumor at the first cystoscopic examination. The older age groups (C and D) had high stage and high grade tumor at the first roentgenological examination and transurethral biopsy or resection. The 5-year recurrence free rate after transurethral resection of bladder tumor (TUR-BT) of the older age group (D group) was lower than that of the other groups. The 5-year survival rate of older age group was lower than that of the younger age group. However, no statistical significance between the age groups existed concerning high grade or high stage tumor and survival after total cystectomy. We clarified here that the clinical features of elderly patients who have bladder cancer were significantly different from those of younger patients. Otherwise the prognosis of patients who have high grade and/or high stage bladder cancer were demonstrated to be poor regardless of age.(ABSTRACT TRUNCATED AT 250 WORDS)
PubMed ID: 8285161
Appears in Collections:Vol.39 No.12

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