Urinary tract infection and blood P1 antigen: preliminary report

Abstract

血液型P1抗原と尿路感染症(UTI)との関係を調べた.対象は正常人11例, UTI 26例で, 後者の内訳は上部尿路感染症4例, 下部尿路感染症22例であった.P1抗原の検出方法はLombergの方法に従った.(1)正常人のP1抗原検出率は3/11例であるが, UTI群では14/26例と高値を示し有意であった.(2)過去1年間にUTIを来たした回数では, 2回以上UTIを来たした例にP抗原検出率が高かった.(3)臨床分離菌は, E, coliを認めた7例中2例にP抗原を検出したが, Proteus, Klebsiella, Serratia, Preudomonasを認めた例はいずれも検出しえなかった

A clinical study was made on the relationship between the blood type P1 antigen and urinary tract infection (UTI). The blood type P1 antigen could be detected in 3 out of 11 healthy Japanese volunteers (27.2%), and in 54% of the UTI patients as a whole. Classified by the type of infection, it could be detected in 3 out of 4 patients with upper UTI (75%) and in 11 out of 22 patients with lower UTI (50%). These incidences were higher than that of healthy volunteers, the difference being statistically significant. The relationship between the annual frequency of UTI and the positive detection of P1 antigen was examined. The patients who had been exposed to UTI twice or more a year proved to have a higher detection rate (61%), than the other group of patients, the difference being statistically significant. Two of the patients with E. coli detected as a clinical isolate proved to have the P1 antigen.