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DCフィールド | 値 | 言語 |
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dc.contributor.author | 山中, 英寿 | ja |
dc.contributor.author | 牧野, 武雄 | ja |
dc.contributor.author | 熊坂, 文成 | ja |
dc.contributor.author | 志田, 圭三 | ja |
dc.contributor.alternative | YAMANAKA, Hidetoshi | en |
dc.contributor.alternative | MAKINO, Takeo | en |
dc.contributor.alternative | KUMASAKA, Fuminari | en |
dc.contributor.alternative | SHIDA, Keizo | en |
dc.date.accessioned | 2010-06-02T01:36:06Z | - |
dc.date.available | 2010-06-02T01:36:06Z | - |
dc.date.issued | 1984-04 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/118151 | - |
dc.description.abstract | The clinical efficacy of (D-Leu6)-des Gly-NH2(10)-LH X RH ethylamide (Leuprolide) against prostatic cancer was evaluated at the end of twelve weeks of administration of a daily dose of 20 mg subcutaneous injection to 22 patients with prostatic cancer. Of these 22 patients, 19 were previously non-treated and 3 had reactivated cancer. Complete regression was obtained in all patients with stage B or C cancer. Also, in 5 out of 12 previously non-treated patients with stage D cancer, Leuprolide administration proved to be effective for controlling prostatic cancer. However, Leuprolide therapy produced only stable effects at best in 3 patients who had reactivated cancer. It has no side effect and should be recommended as a drug of first choice in the treatment of previously non-treated prostatic cancer. It can be assumed from the present studies that the efficacy of this agent against prostatic cancer is mainly the result of its inhibitory effect on hypothalamo-pituitary testicular system, i.e., a medical castration effect. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Prostatic cancer | en |
dc.subject | LH.RH agonist | en |
dc.subject.ndc | 494.9 | - |
dc.title | 前立腺癌に対する(D-Leu6)-des Gly-NH210-LH・RH ethylamide (Leuprolide)の臨床効果 | ja |
dc.title.alternative | Clinical efficacy of (D-Leu6)-des Gly-NH2(10)-LHRH ethylamide against prostatic cancer | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 30 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 545 | - |
dc.identifier.epage | 560 | - |
dc.textversion | publisher | - |
dc.sortkey | 15 | - |
dc.address | 群馬大学医学部泌尿器科学教室 | ja |
dc.address | 群馬大学医学部泌尿器科学教室 | ja |
dc.address | 群馬大学医学部泌尿器科学教室 | ja |
dc.address | 群馬大学医学部泌尿器科学教室 | ja |
dc.address.alternative | the Department of Urology, School of Medicine, G, unma University | en |
dc.address.alternative | the Department of Urology, School of Medicine, G, unma University | en |
dc.address.alternative | the Department of Urology, School of Medicine, G, unma University | en |
dc.address.alternative | the Department of Urology, School of Medicine, G, unma University | en |
dc.identifier.pmid | 6435416 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.30 No.4 |
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