上部尿路結石症患者における経口カルシウム負荷試験の検討

Abstract

上部尿路結石症55例にCa負荷試験をおこなった.1)尿路結石患者の尿中Caの排泄量は, コントロール群に比し高く, 有意差であった.2)特発性高Ca尿症は, 13例に認め, Ca負荷試験の成績より4例はabsorptive hypercalciuria, 6例はrenal hypercalciuriaと考え, 3例は判定不能であった.Renal hypercalciuriaの6例中5例は, 再発性あるいは多発性結石群であった

An oral calcium loading test was performed on 55 patients with upper urinary tract stones to find absorptive or renal hypercalciuria. The mean urinary calcium excretion level of this patient group was significantly greater than that of a control group of 10 patients without abnormal upper urinary tract. Idiopathic hypercalciuria defined as more than 250 mg per day in males and more than 200 mg per day in females was observed in 13 patients; 4 patients with absorptive hypercalciuria, 6 patients with renal hypercalciuria and 3 patients of origin-unknown hypercalciuria. Five of the 6 patients with renal hypercalciuria had recurrent and/or multiple urolithiasis. From these results, this test was considered to be useful in the discrimination between absorptive and renal hypercalciuria.