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このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 30_953.pdf | 1.94 MB | Adobe PDF | 見る/開く |
完全メタデータレコード
| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | 藤田, 公生 | ja |
| dc.contributor.alternative | FUJITA, Kimio | en |
| dc.date.accessioned | 2010-06-02T01:39:09Z | - |
| dc.date.available | 2010-06-02T01:39:09Z | - |
| dc.date.issued | 1984-07 | - |
| dc.identifier.issn | 0018-1994 | - |
| dc.identifier.uri | http://hdl.handle.net/2433/118220 | - |
| dc.description.abstract | A two-compartment model of kidney cells is designed. The first compartment is the cytoplasm, the other is a large organelle fraction consisting of lysosomes and mitochondria. Drugs easily accumulated in the second compartment are considered to be harmful to the kidney. Although small molecular antibiotics move across membranes, they reach a certain equilibrium within 30 minutes. Therefore reproducible values of antibiotic concentrations in both fractions can be obtained. The two-compartment model provides a new approach to pharmacokinetic study at a subcellular level. | en |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | jpn | - |
| dc.publisher | 泌尿器科紀要刊行会 | ja |
| dc.subject | Antibiotics | en |
| dc.subject | Kidney | en |
| dc.subject | Pharmacokinetics | en |
| dc.subject | Subcellular fraction | en |
| dc.subject.ndc | 494.9 | - |
| dc.title | 抗生物質の腎分画内濃度 | ja |
| dc.title.alternative | Antibiotic concentration in kidney cell fractions | en |
| dc.type | departmental bulletin paper | - |
| dc.type.niitype | Departmental Bulletin Paper | - |
| dc.identifier.ncid | AN00208315 | - |
| dc.identifier.jtitle | 泌尿器科紀要 | ja |
| dc.identifier.volume | 30 | - |
| dc.identifier.issue | 7 | - |
| dc.identifier.spage | 953 | - |
| dc.identifier.epage | 956 | - |
| dc.textversion | publisher | - |
| dc.sortkey | 16 | - |
| dc.address | 国立病院医療センター泌尿器科 | ja |
| dc.address.alternative | the Department of Urology, National Medical Center Hospital | en |
| dc.identifier.pmid | 6507212 | - |
| dcterms.accessRights | open access | - |
| dc.identifier.pissn | 0018-1994 | - |
| dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
| dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
| 出現コレクション: | Vol.30 No.7 | |
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