An evaluation of blood serotonin in infertile male patients

Abstract

45症例につき検討した.乏精子症患者のセロトニンの平均値は80.1±33.0 ng/dl, 無精子症患者のそれは107.0±41.2 ng/dlであり, その差は有意であった.精索静脈瘤のある例のセロトニン値の平均は83.4 ng/dlであり, ない例のそれは94.0 ng/dl, また, 慢性副睾丸炎などの閉塞機転のある患者での平均値は80.3 ng/dl, ない例のそれは92.1 ng/dlであったが, それぞれ有意差は認めなかった

This study was made to clarify what role serotonin plays in testicular function. Forty-five infertile men were subjected to the study; 30 had oligozoospermia and the others had azoospermia. Blood serotonin levels of the patients were determined and the relationship between blood serotonin levels and other clinical findings was evaluated statistically. The mean value of blood serotonin in oligozoospermia was 80.1 +/- 33.0 ng/dl and that of azoospermia was 107.0 +/- 41.2 ng/dl, the difference being significant statistically (p less than 0.05). The blood serotonin level of the patients who had varicocele was 83.4 ng/dl and that of those who did not 94.0 ng/dl, there being no statistically significant difference between them. The level in the patients who had obstructive lesions was 80.3 and that in those who did not 92.1 ng/dl, there being no significant difference between them. The blood serotonin level proved to be unrelated with other clinical findings.