好酸球性膀胱炎の臨床研究 : その1. 好酸球性膀胱炎の定義に関する検討 (1) 好酸球浸潤に関する組織学的検討

Abstract

1)好酸球増加例5例につき, 好酸球増加部位200倍5視野における1視野平均好酸球数は20～50個の範囲にあり全円形細胞数における好酸球の割合が50%以上であった.全視野において, 200倍毎視野に数個あるいは数視野に20個以上認められた.2)対照例の200倍5視野における1視野平均好酸球数は1個以下であり, 全円形細胞との比率は5%以下であった.また対照例は全視野において数視野に約5個以下であり, 円形細胞との比率は5%以下であった.3)好酸球増加例5例を好酸球性膀胱炎とした

Eosinophilic cystitis is a disease accompanied by prominent increase in the number of eosinophils in the vesical wall, but whether it is diagnosable from the number of eosinophils has not been clear. We made histological observations in 5 cases thought to have elevated eosinophil count and 13 control cases. We counted the eosinophils in the 5 fields we considered to be the place eosinophils were most abundant under 200 times magnification, and an average of 20 to 50 eosinophils were found in each field. The ratio of eosinophils in the same field to all round cell infiltration was from 36 to 85%. In 2 of the 5 cases, more than 20 eosinophils were found in some fields and the ratio to all round cell infiltration was under 5%. In the remaining one case from 5 to 20 eosinophils were found in some fields, but the ratio to round cell infiltration was over 20%. On the other hand, in the 13 control cases, the average number of eosinophils was one per field and the ratio to all round cell infiltration was under 5% in the 5 fields we considered to be the place eosinophils were most abundant. Less than 5 eosinophils were found in any of the fields and the ratio to all round cell was under 5%. From these results, the 5 cases thought to have elevated eosinophil count were diagnosed to be eosinophilic cystitis.