膀胱移行上皮癌に対する膀胱全摘除術の治療成績

Abstract

1) 1974年4月15日より9年間に, 自治医科大学泌尿器科学教室において膀胱全摘除術を施行した膀胱移行上皮癌53例の遠隔成績をまとめた.2) 53例全例の5年相対生存率は58.2%(標準誤差8.0%)であった.3) gradeおよびstage別に相対生存率を検討すると, low grade群で5年相対生存率が116%, high grade群で33.8%, またlow stage群で3年相対生存率が88.4%, high stage群で16.6%となり, low grade群, low stage群の予後が有意に良好であった.4)癌死率はlow grade群で0%, low stage群で17.2%であったが, high grade群では50.0%, high stage群では63.6%と高かった.5)術後死亡は3例あり, 穿孔性腹膜炎1例, 大量吐血1例, 急性腎不全1例で, 術後死亡率は5.7%であった

The late results on 53 patients with bladder transitional cell cancer, who were treated by total cystectomy at the Department of Urology, Jichi Medical School between 1974 through 1983, were reviewed. The ages ranged from 28 to 78 years old, with an average of 61.8 years. There were 48 men and 5 women, with a male to female ratio of 9.6:1. The relative 5-year survival rate was 58.2% as a whole, that of patients with low grade cancer (grade 1 and 2) was 116%, and that of patients with high grade cancer (grade 3) was 33.8%. A significant difference was observed (p less than 0.01). The relative 3-year survival rate of low stage cancer (pT1 and pT2) was 88.4%, that of high stage cancer (pT3 and pT4) was 16.6%, a significant difference being observed (p less than 0.01). The post operative mortality rate was 5.7%.