前立腺炎症例におけるN-acetyl-β-glucosaminidaseの変動について

Abstract

前立腺炎症例における, 尿中NAG, 又は前立腺マッサージ後の尿におけるNAGを測定した.その結果, 尿中NAG値は, 健常人に比べ明らかに高い値を示しただけでなく, 病態の推移に非常によく一致していた.尿中NAGの臨床的評価の際, 前立腺の病変も考慮にいれることが大切である.尿中NAGの経時的測定は, 前立腺炎の病変の(その中でも急性前立腺炎の)一指標になる

NAG was measured before and after treatment and compared in 11 acute prostatitis patients, 13 chronic prostatitis patients and 10 healthy volunteers. Urinary NAG before treatment was 34.1 +/- 18.4 U/l in the acute prostatitis patients and was significantly higher than that in the healthy volunteers, which was 5.1 +/- 1.2 U/l. It was 8.5 +/- 3.2 U/l in the chronic prostatitis patients. Urinary NAG after treatment decreased and was 7.6 +/- 4.4 U/l and 6.7 +/- 1.7 U/l in the acute and chronic prostatitis groups, respectively. These results suggest that urinary NAG is useful in evaluating the changes in the condition of prostatitis and in diagnosing prostatitis, especially acute prostatitis.