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dc.contributor.author | 塚本, 泰司 | ja |
dc.contributor.author | 熊本, 悦明 | ja |
dc.contributor.author | 大村, 清隆 | ja |
dc.contributor.author | 恒川, 琢司 | ja |
dc.contributor.author | 山崎, 清仁 | ja |
dc.contributor.alternative | Tsukamoto, Taiji | en |
dc.contributor.alternative | Kumamoto, Yoshiaki | en |
dc.contributor.alternative | Ohmura, Kiyotaka | en |
dc.contributor.alternative | Tsunekawa, Takuji | en |
dc.contributor.alternative | Yamazaki, Kiyohito | en |
dc.date.accessioned | 2010-06-02T02:11:25Z | - |
dc.date.available | 2010-06-02T02:11:25Z | - |
dc.date.issued | 1986-07 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/118864 | - |
dc.description.abstract | Between August, 1968 and March, 1985, we treated 27 patients with testicular seminoma. The histopathological type was typical seminoma in 23 (85%) and anaplastic seminoma in 4 (15%). Their clinical stages were classified into stage I for 17 patients (63%), 7 patients (25%) in II and 3 (12%) in III. Tumor markers, alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG-beta), were determined in 16 patients. None of them showed an elevated level of AFP, but 7 (43.8%) had elevated hCG-beta in the peripheral vein. The hCG-beta in the spermatic vein on the tumor side was elevated in 12 out of 14 patients (88.9%). The hCG-beta level in the spermatic vein on the tumor side was significantly higher than that in the peripheral vein in 10 patients with stage I seminoma. This finding suggests that the determination of hCG-beta in the spermatic vein would give us more accurate information on the production of hCG-beta in seminoma. Although the elevation of the hCG-beta level in pure seminoma has been supposed to be a poor prognostic factor, our results indicated that a mild to moderate elevation of hCG-beta in stage I seminoma did not always imply a poor clinical course, first, because none of these 10 patients, even with an elevated hCG-beta, who underwent retroperitoneal lymph node dissection (RPLND), had microscopic metastasis, and second, because none of these have had a recurrence of the disease up to now.(ABSTRACT TRUNCATED AT 250 WORDS) | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Chorionic Gonadotropin/blood | en |
dc.subject | Chorionic Gonadotropin, beta Subunit, Human | en |
dc.subject | Combined Modality Therapy | en |
dc.subject | Dysgerminoma/blood/surgery | en |
dc.subject | Humans | en |
dc.subject | Lymph Node Excision | en |
dc.subject | Male | en |
dc.subject | Peptide Fragments/blood | en |
dc.subject | Retroperitoneal Space | en |
dc.subject | Testicular Neoplasms/blood/surgery | en |
dc.subject.ndc | 494.9 | - |
dc.title | Seminoma 27例の検討 : 特にstage1seminomaにおけるHCG-β測定の意義とstage1seminomaに対する後腹膜リンパ節郭清術の検討 | ja |
dc.title.alternative | Clinical studies of testicular tumor. I. Analysis of 27 patients with seminoma: the clinical significance of hCG-beta determination and of retroperitoneal lymph node dissection for stage I patients | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 32 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 989 | - |
dc.identifier.epage | 997 | - |
dc.textversion | publisher | - |
dc.sortkey | 10 | - |
dc.address | 札幌医科大学泌尿器科学教室 | ja |
dc.address.alternative | The Department of Urology, Sapporo Medical College | en |
dc.identifier.pmid | 2430436 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.32 No.7 |
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