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Title: Testosterone投与後の"はねかえり現象"に関する実験的研究 --Flow cytometry (FCM)による睾丸組織内DNA量分布測定--
Other Titles: DNA flow cytometric evaluation of spermatogenesis of the rebound phenomenon with testosterone in adult male rats
Authors: 磯山, 理一郎  KAKEN_name
Author's alias: Isoyama, Riichiro
Keywords: Animals
DNA/analysis
Flow Cytometry
Male
Rats
Rats, Inbred Strains
Spermatogenesis/drug effects
Testis/analysis
Testosterone/pharmacology
Time Factors
Issue Date: Jul-1986
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 32
Issue: 7
Start page: 981
End page: 988
Abstract: To examine the effects of the rebound phenomenon on the rat testis, adult male Wistar rats were treated with 0.3 mg/day of testosterone propionate (TP) for 39 days. Observations were made on 0, 26, 52, 78 and 104 days following the TP treatment. The response of the testis was investigated by determining the testicular weight and DNA flow cytometric analysis in the testicular cells. The % haploid cells (spermatids) increased at the 52nd and the 78th day after TP treatment, and were equal to the rate of the control group. The % diploid cells and % tetraploid cells showed no change. The duration of the rebound phenomenon was about 2-2.5 months.
URI: http://hdl.handle.net/2433/118865
PubMed ID: 3776775
Appears in Collections:Vol.32 No.7

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