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タイトル: | 複雑性尿路感染症に対するCefoxitinとAmikacinの併用療法の臨床的評価 |
その他のタイトル: | Clinical evaluation of combination therapy with cefoxitin and amikacin in complicated urinary tract infections |
著者: | 坂下, 茂夫 信野, 祐一郎 浅野, 嘉文 坪, 俊輔 今中, 香里 宮部, 憲朗 永森, 聡 高橋, 康英 小柳, 知彦 |
著者名の別形: | SAKASHITA, Shigeo SHINNO, Yuichirou ASANO, Yoshifumi TUBO, Syunsuke IMANAKA, Kaori MIYABE, Norio NAGAMORI, Satoshi TAKAHASHI, Yasuhide KOYANAGI, Tomohiko |
キーワード: | Complicated UTI Cefoxitin Amikacin |
発行日: | Oct-1986 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 32 |
号: | 10 |
開始ページ: | 1547 |
終了ページ: | 1550 |
抄録: | The clinical efficacy of combination therapy using Cefoxitin (CFX) and Amikacin (AMK) was studied in 19 patients with complicated urinary tract infections. Patients received 2 g of CFX i.v. and 100 mg of AMK i.m. twice a day. The overall clinical efficacy of treatment was evaluated by the criteria proposed by the UTI Committee, Japan, as excellent, moderate or poor. The overall clinical efficacy was excellent in 89%, moderate in 5% and poor in 5% of the patients. Of the 21 strains isolated from the patients, 20 strains (95%) were eradicated. No subjective side effects were observed. Drug-related aggravation in laboratory tests were observed slight elevations of glutomic-oxalacefic transaminase, glutamic-pyruvic transaminase and alkaliphosphatase in 2 cases, but all of them were minimal and reversible. Underlying condition-related aggravation was observed a slight elevation of BUN and creatinine clearance in 1 case. These results suggest that the combination therapy with CFX and AMK might be useful in the treatment of complicated urinary tract infections. |
URI: | http://hdl.handle.net/2433/118926 |
PubMed ID: | 3565192 |
出現コレクション: | Vol.32 No.10 |
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