塩酸パパベリンの陰茎海綿体局注後の勃起状態に対する塩酸エチレフリンの効果

Abstract

1)インポテンスの4例に対して塩酸パパベリン40 mgを陰茎海綿体内へ局注後, 30分目ないし80分目の完全勃起状態に対して塩酸エチレフリン1 mgないし2 mgを局注し, 勃起状態の消退が得られた.2)塩酸エチレフリンの使用量は塩酸パパベリン40 mg局注の場合2 mgが適当量と思われた.3)塩酸エチレフリン局注後, 全例とも特に副作用は認められなかった

Intracavernous injection of etilefrine hydrochloride (1 or 2 mg) was performed on four patients with fully erected penis after intracavernous injection of 40 mg of papaverine hydrochloride. One case needed three injections of etilefrine hydrochloride (1 mg), but the erection disappeared in the other three cases within 10 minutes after a single injection of 2 mg of etilefrine hydrochloride. The injection resulted in complete detumescence and relief of the erection in all cases. These observations strongly suggest that the intracavernous injection of etilefrine hydrochloride is effective in treating not only iatrogenic priapism but also priapism due to other etiologies. Also, it might be useful to control erection time after intracavernous injection therapy for impotence.