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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 33_329.pdf | 358.57 kB | Adobe PDF | 見る/開く |
完全メタデータレコード
| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | 郷司, 和男 | ja |
| dc.contributor.author | 浜見, 学 | ja |
| dc.contributor.author | 守殿, 貞夫 | ja |
| dc.contributor.alternative | GOHJI, Kazuo | en |
| dc.contributor.alternative | HAMAMI, Gaku | en |
| dc.contributor.alternative | KAMIDONO, Sadao | en |
| dc.date.accessioned | 2010-06-02T02:18:55Z | - |
| dc.date.available | 2010-06-02T02:18:55Z | - |
| dc.date.issued | 1987-03 | - |
| dc.identifier.issn | 0018-1994 | - |
| dc.identifier.uri | http://hdl.handle.net/2433/119084 | - |
| dc.description.abstract | The inhibitory effect of human-recombinant tumor necrosis factor (Hu-rec-TNF) alone or in combination with human recombinant gamma-interferon (rec gamma-IFN), doxorubicin (ADM) or cis-platinum (CDDP) was studied for two human renal cell carcinoma lines (KO-RCC-1 and RCC-nu-1 cells). Hu-rec-TNF inhibited the cell growth of KO-RCC-1 cells in a dose- and time-dependent manner. The inhibitory effect was seen 48 hours after the treatment with Hu-rec-TNF alone. The effect of Hu-rec-TNF was cytotoxic in our experiment. On the other hand, Hu-rec-TNF did not inhibit the cell growth of RCC-nu-1 cells. There were sensitive and resistant cells in renal cell carcinoma. In KO-RCC-1 cells, Hu-rec-TNF enhanced the inhibitory effect of rec gamma-IFN, ADM or CDDP. On the other hand, Hu-rec-TNF did not enhance the inhibitory effect of rec gamma-IFN, ADM or CDDP in RCC-nu-1 cells. In our experiment, the combined treatment with Hu-rec-TNF and rec gamma-IFN, ADM or CDDP was useful in human renal cell carcinoma which was sensitive for Hu-rec-TNF. | en |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | jpn | - |
| dc.publisher | 泌尿器科紀要刊行会 | ja |
| dc.subject | Human recombinant TNF | en |
| dc.subject | Renal cell carcinoma | en |
| dc.subject.ndc | 494.9 | - |
| dc.title | ヒト腎細胞癌培養株細胞に対する遺伝子組み換えヒトTNFの抗腫瘍活性および遺伝子組み換えヒトγ-lnterferon,Doxorubicin,Cis-platinumとの併用効果 | ja |
| dc.title.alternative | Anti-neoplastic activity of a human recombinant tumor necrosis factor (Hu-rec-TNF) alone or in combination with human recombinant gamma-interferon, doxorubicin or cis-platinum on a human renal cell carcinoma line | en |
| dc.type | departmental bulletin paper | - |
| dc.type.niitype | Departmental Bulletin Paper | - |
| dc.identifier.ncid | AN00208315 | - |
| dc.identifier.jtitle | 泌尿器科紀要 | ja |
| dc.identifier.volume | 33 | - |
| dc.identifier.issue | 3 | - |
| dc.identifier.spage | 329 | - |
| dc.identifier.epage | 335 | - |
| dc.textversion | publisher | - |
| dc.sortkey | 01 | - |
| dc.address | 神戸大学医学部泌尿器科学教室 | ja |
| dc.address | 神戸大学医学部泌尿器科学教室 | ja |
| dc.address | 神戸大学医学部泌尿器科学教室 | ja |
| dc.address.alternative | Department of Urology, Kobe University School of Medicine | en |
| dc.address.alternative | Department of Urology, Kobe University School of Medicine | en |
| dc.address.alternative | Department of Urology, Kobe University School of Medicine | en |
| dc.identifier.pmid | 3113191 | - |
| dcterms.accessRights | open access | - |
| dc.identifier.pissn | 0018-1994 | - |
| dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
| dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
| 出現コレクション: | Vol.33 No.3 | |
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