A study of cryptorchidism. III: The histochemistry of complex carbohydrates in the testes of cryptorchid patients

Abstract

3～37歳の停留精巣患者23例の停留精巣および対側陰嚢内精巣において, 光顕組織化学的方法にて複合糖質の変化を観察し, さらに正常精巣組織と比較した.停留精巣精細管壁及び間質では, 正常精巣に比べ酸性ムコ多糖(精細管壁:コンドロイチン硫酸A及びC, 間質:コンドロイチン硫酸B)が減少し, 特に精細管壁において顕著であった.なお, 患側精細管上皮においては, 思春期前から思春期以後を通じ, グリコーゲン及びガラクトース含有量の減少が認められた

The complex carbohydrates in the undescended and contralateral scrotal testes of patients with cryptorchidism, were examined by light microscopic histochemical methods, in comparison with those of normal testes. In the undescended testes, histochemical reactions for acidic and neutral complex carbohydrates were apparently weaker than in the normal testes, especially pronounced in the seminiferous tubular walls. In the germinal and supporting cells of the undescended testes, the amount of galactose residues in the complex carbohydrates decreased from the prepubertal to post-pubertal periods. Periodic acid-Schiff reaction also revealed a decrease in the glycogen content in the germinal and supporting cells of the undescended testes from pre-pubertal to post-pubertal periods.