東海大学病院泌尿器科における尿中分離細菌について 第4報: 1983～1984年の分離細菌とディスク感受性

Abstract

1983年1月から2年間に, 受診もしくは入院した患者尿中から105個/ml以上検出された細菌について検討した.今回は同一患者からの同一と思われるものは除外したが, 外来で2, 222株, 入院から507株検出した.外来ではE. coliが最も多く, 21.4%, 続いてEnterococcus 11.3%, Proteus sp. 10.4%, P. aeruginosa 10.0%, Alcalignes sp. 5.6%, S. epidermidis 4.2%, K. pneumoniae 3.7%の順であった.入院ではEnterococcus 20.3%, P. aeruginosa 16.2%, E. coli 9.1%, Enterobacter sp. 7.7%, S. epidermidis 7.5%, Proteus sp. 5.0%, S. marcescence 4.9%の順であった.薬剤感受性試験の結果, 前報と比較できる薬剤は限られているが, 外来のほうではそれほど大きな変化はなく, 入院のほうでは主要な菌種にGMの感受性立低下があった.また, NA, TGでも感受性率が低下したものが多かった.新しく採用された薬剤についてはほぼ妥当と思われる成績を得た

The statistics and drug sensitivity tests of bacterial florae isolated from the urinary tract in 1983 and 1984 were reviewed. Of the 2, 222 strains isolated from outpatients, 593 (26.7%) were gram positive cocci, 21.4% were E. coli, 11.3% were Enterococcus, 10.4% were Proteus sp., 10.0% were P. aeruginosa, 5.6% were Alcaligenes sp., 4.2% were S. epidermidis and the rest were others. Of the 507 strains isolated from hospitalized patients, 107 (33.5%) were gram positive cocci, 20.3% were Enterococcus, 16.2% were P. aeruginosa, 9.1% were E. coli, 7.7% were Enterobacter sp. 7.5% were S. epidermidis, 4.9% were Proteus sp., S. marcescence and the rest were others. The percentage of E. coli, K. pneumoniae and S. epidermidis detected in the isolates from the outpatients and that of K. pneumoniae, Proteus sp. and S. epidermidis detected from the inpatients were lower than in previous reports. The percentage of P. aeruginosa and Enterococcus detected in the isolates from both groups of patients were higher than in previous reports. The major isolates (9 species) from the outpatients were more susceptible to the antimicrobial agents tested than those from the inpatients. The susceptibility of gentamicin, tetracycline and nalidixic acid to the major isolates was lower than in previous reports. During the past 2 years, we have been routinely using on inpatients the so-called new generation cefem antibiotics to treat urinary tract infections. This might be why the number of isolates of Enterococcus has increased especially in the isolates from inpatients.