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33_1167.pdf | 3.67 MB | Adobe PDF | 見る/開く |
タイトル: | 進行膀胱癌に対するアンギオテンシンH併用,シスプラチン(CDDP),アクラシノマイシン(ACR)動注療法 |
その他のタイトル: | Treatment of advanced bladder cancer with intra-arterial infusion of cisplatinum (CDDP) and aclacinomycin (ACR), combined with angiotensin II |
著者: | 朝日, 俊彦 ![]() 武田, 克治 ![]() 早田, 俊司 ![]() 大北, 健逸 ![]() 赤沢, 信幸 ![]() 津川, 昌也 ![]() |
著者名の別形: | ASAHI, Toshihiko TAKEDA, Katsuji HAYATA, Shunji OKITA, Kenitsu AKAZAWA, Nobuyuki TSUGAWA, Masaya |
キーワード: | Angiotensin II Intra-arterial infusion therapy Bladder cancer |
発行日: | Aug-1987 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 33 |
号: | 8 |
開始ページ: | 1167 |
終了ページ: | 1171 |
抄録: | Ten patients with advanced bladder cancer were treated with intra-arterial infusion therapy. The patients consisted of nine males and one female between 55 and 82 years old (median: 70 years). In all patients, cisplatinum (CDDP) (2 mg/kg), aclacinomycin (ACR) (0.5 mg/kg) and Angiotensin II (25 mg) were infused via the internal iliac artery for a period of about 30 minutes. Seven patients also received X-ray therapy with a linac. The efficacy of this therapy was assessed by computed tomographic scanning, sonography and cystoscopy. As a result of this assessment, 2 patients were rated complete response "(CR)", 6 partial response (PR) (showing 50% or more reduction in the lesion) and 2 no change "(NC)". To compare the efficacy of this therapy for two histopathologically defined groups of patients (patients with grades 2 and 3 cancer), one patient was rated "CR", four "PR" and two "NC" in the grade 3 group (total 7 patients), while one was rated "CR" and two "PR", in the grade 2 group (total 3 patients). In effective cases, pollakiuria and miction pain disappeared shortly following intra-arterial infusion therapy. As for side effects of the therapy, mild nausea or vomiting was observed in all patients, while leukopenia was noted in one patient. |
URI: | http://hdl.handle.net/2433/119243 |
PubMed ID: | 3425516 |
出現コレクション: | Vol.33 No.8 |
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