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DCフィールド | 値 | 言語 |
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dc.contributor.author | 大川, 光央 | ja |
dc.contributor.author | 中嶋, 孝夫 | ja |
dc.contributor.author | 徳永, 周二 | ja |
dc.contributor.author | 川口, 正一 | ja |
dc.contributor.author | 菅田, 敏明 | ja |
dc.contributor.author | 久住, 治男 | ja |
dc.contributor.author | 上野, 一恵 | ja |
dc.contributor.author | 渡辺, 邦友 | ja |
dc.contributor.alternative | OHKAWA, Mitsuo | en |
dc.contributor.alternative | NAKAJIMA, Takao | en |
dc.contributor.alternative | TOKUNAGA, Shuji | en |
dc.contributor.alternative | KAWAGUCHI, Shoichi | en |
dc.contributor.alternative | SUGATA, Toshiaki | en |
dc.contributor.alternative | HISAZUMI, Haruo | en |
dc.contributor.alternative | UENO, Kazue | en |
dc.contributor.alternative | WATANABE, Kunitomo | en |
dc.date.accessioned | 2010-06-02T02:36:18Z | - |
dc.date.available | 2010-06-02T02:36:18Z | - |
dc.date.issued | 1988-01 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/119422 | - |
dc.description.abstract | 1985年に受診した男子GU患者89例の尿道smearから分離された淋菌89株中12株がPPNGと判定され, これらPPNGはPCG, AMPCに高度耐性を示し, CTXのMICが最も低値を示した.また, 89例中60例にC. trachomatisの検索を施行し, 11例が陽性であった | ja |
dc.description.abstract | Eighty-nine isolates of Neisseria gonorrhoeae from 89 male urethritis patients were studied for beta-lactamases (penicillinase) production, and their susceptibilities to benzylpenicillin, amoxicillin, piperacillin, clavulanic acid/amoxicillin (Augmentin), cephalexin, cefotaxime, spectinomycin and minocycline were determined by an agar plate-dilution method. Penicillinase activity was tested by a chromogenic cephalosporin method with nitrocefin as substrate (CefinaseTM discs, BBL, USA) and by a paper strip acidimetric method with benzylpenicillin as substrate (beta-Lactamase detection papers, Oxoid, UK). In addition, 60 of the 89 patients were examined for Chlamydia trachomatis, using fluorescein-labeled monoclonal antibodies (Direct specimen test; Micro TrakTM, Syva Co., USA). Penicillinase-producing N. gonorrhoeae (PPNG) were found in 12 of the 89 strains (13.5%). Although all these strains of PPNG were highly resistant to benzylpenicillin and amoxicillin, the minimum inhibitory concentrations (MICs) of Augmentin markedly decreased. Piperacillin was highly active against not only non-PPNG but also PPNG strains. More than half the isolates were resistant to cephalexin (MICs greater than or equal to 12.5 micrograms/ml) while all strains including non-PPNG and PPNG were fully sensitive to cefotaxime (MICs less than or equal to 0.20 microgram/ml). Spectinomycin and minocycline had MIC ranges of 6.25 to 25 micrograms/ml and 0.01 to 3.13 micrograms/ml, respectively; the ranges for non-PPNG and PPNG strains were fairly similar. C. trachomatis was detected in 11 (18.3%) out of 60 patients examined. The increasing incidence of PPNG and coexisting chlamydial infection should be taken into account in the treatment of gonococcal urethritis. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Male urethritis | en |
dc.subject | Penicillinase-producing Neisseria gonorrhoeae (PPNG) | en |
dc.subject | Susceptibility of antimicrobial agents | en |
dc.subject.ndc | 494.9 | - |
dc.title | 男子尿道炎患者から分離されたpenicillinase-producing Neisseriagonorrhoeae (PPNG) について | ja |
dc.title.alternative | Detection of penicillinase-producing Neisseria gonorrhoeae from male patients with urethritis | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 34 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 130 | - |
dc.identifier.epage | 136 | - |
dc.textversion | publisher | - |
dc.sortkey | 20 | - |
dc.address | 金沢大学医学部泌尿器科学教室 | ja |
dc.address | 金沢大学医学部泌尿器科学教室 | ja |
dc.address | 金沢大学医学部泌尿器科学教室 | ja |
dc.address | 金沢大学医学部泌尿器科学教室 | ja |
dc.address | 金沢大学医学部泌尿器科学教室 | ja |
dc.address | 金沢大学医学部泌尿器科学教室 | ja |
dc.address | 岐阜大学医学部嫌気性菌実験施設 | ja |
dc.address | 岐阜大学医学部嫌気性菌実験施設 | ja |
dc.address.alternative | the Department of Urology, School of Medicine, Kanazawa University | en |
dc.address.alternative | the Department of Urology, School of Medicine, Kanazawa University | en |
dc.address.alternative | the Department of Urology, School of Medicine, Kanazawa University | en |
dc.address.alternative | the Department of Urology, School of Medicine, Kanazawa University | en |
dc.address.alternative | the Department of Urology, School of Medicine, Kanazawa University | en |
dc.address.alternative | the Department of Urology, School of Medicine, Kanazawa University | en |
dc.address.alternative | the Institute of Anaerobic Bacteriology, Gifu University School of Medicine | en |
dc.address.alternative | the Institute of Anaerobic Bacteriology, Gifu University School of Medicine | en |
dc.identifier.pmid | 3132029 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.34 No.1 |
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