慢性前立腺炎と前立腺炎様症候群の臨床的研究 第2報: 治療効果の検討

Abstract

慢性前立腺炎229例(細菌性29例・非細菌性200例)と前立腺炎様症候群238例を対象に治療の有効性を検討した.1)病型別臨床成績は, 慢性前立腺炎で77.3%(細菌性82.8%・非細菌性76.5%)に対し, 前立腺炎様症候群で53.8%で, 有意差(p<0.01)をみた.2)薬物療法は, 前立腺炎様症候群では無効だが, 慢性細菌性前立腺炎では化学療法と消炎剤の併用で良好, 慢性非細菌性前立腺炎では化学療法が有意(p<0.05)に有用であった.3)慢性前立腺炎の化学療法の効果は, 細菌性・非細菌性ともにST合剤, Tetracycline系, Cephem系の順であったが, 有意差はない.4)前立腺マッサージは総じて有用で, 慢性非細菌性前立腺炎(p<0.05), 前立腺炎様症候群(p<0.01)に効果が高い.5)簡易精神療法は前立腺炎様症候群のうちpsychosomaticな要素の強い症例に有意(p<0.01)な有用性を認めた

We treated 229 cases of chronic prostatitis (bacterial in 29, non-bacterial in 200) and 238 cases of prostatitis-like syndrome and evaluated the clinical efficacy. Clinical efficacy was seen in 77.3% of the chronic prostatitis cases (82.8% bacterial, 76.5% non-bacterial) and 53.8% of the prostatitis-like syndrome cases, with a statistical difference between these two types of disease (p less than 0.01). Treatment included chemotherapy, anti-inflammation agents and minor tranquilizers. None of them were effective against the prostatitis-like syndrome. On the other hand, combination usage (chemotherapies and anti-inflammation agent) was satisfactory on chronic bacterial prostatitis. Also on chronic non-bacterial prostatitis, chemotherapy was significantly effective (p less than 0.05%). Chemotherapeutic effectiveness against chronic prostatitis (both bacterial and non-bacterial) was high with sulfamethoxazole-trimethoprim, tetracyclines, cephalosporins, nalidixic acid and penicillins in this order. There was no difference among these drugs. Prostatic massage was generally effective especially for chronic non-bacterial prostatitis (p less than 0.05) and prostatitis-like syndrome (p less than 0.01). Light psychological treatment was significantly effective toward some cases of prostatitis-like syndrome with strong psychosomatic factors (p less than 0.01).