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Title: 尿路感染症に対するEnoxacin (ENX)の臨床的検討
Other Titles: Clinical studies on enoxacin in urinary tract infection
Authors: 永井, 信夫  KAKEN_name
金子, 茂男  KAKEN_name
秋山, 隆弘  KAKEN_name
栗田, 孝  KAKEN_name
井口, 正典  KAKEN_name
片岡, 喜代徳  KAKEN_name
Author's alias: Nagai, Nobuo
Kaneko, Shigeo
Akiyama, Takahiro
Kurita, Takashi
Iguchi, Masanori
Kataoka, Kiyonori
Keywords: Administration, Oral
Adolescent
Adult
Aged
Anti-Infective Agents, Urinary/administration & dosage/therapeutic use
Cystitis/drug therapy
Drug Evaluation
Enoxacin/administration & dosage/therapeutic use
Escherichia coli Infections/drug therapy
Female
Humans
Kidney Calculi/complications
Male
Middle Aged
Urinary Tract Infections/drug therapy
Issue Date: Jul-1988
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 34
Issue: 7
Start page: 1283
End page: 1291
Abstract: Enoxacin was administered orally to 49 out-patients with urinary tract infections (UTI) at the doses of 600 mg/day and clinical effects were evaluated. Out of 13 patients with simple acute UTI evaluated by the UTI criteria, the results were excellent in 8 cases and good in 5 cases. Overall effectiveness rate was 100%. Out of 10 patients with simple acute UTI evaluated on over 5-day administration, the results were excellent in 9 cases and good in 1 case. Overall effectiveness rate was 100%. Out of 14 patients with simple acute UTI evaluated by our own criteria because their bacteriological response is unknown, the results were excellent in 7 cases and good in 7 cases. Overall effectiveness rate was 100%. Out of 12 patients with chronic complicated UTI evaluated by the UTI criteria, the results were excellent in 6 cases, good in 3 cases and poor in 3 cases. Overall effectiveness rate was 75.0%. Poor effective cases were mainly found in ones with mixed infection. Sensitivity test using discs did not always correspond to the bacteriological effect in cases with chronic complicated UTI. An adverse reaction was noted in 3 patients (6.1%). Two cases had gastrointestinal symptoms and 1 case had skin eruption. All symptoms were readily improved after discontinuing administration. From the above results, Enoxacin was considered to be a useful agent for urinary tract infection.
URI: http://hdl.handle.net/2433/119624
PubMed ID: 3051955
Appears in Collections:Vol.34 No.7

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