MRI of prostatic cancer: in vivo and in vitro MRI results compared with pathological findings

Abstract

23例の前立腺癌の患者に対しMRIを施行した.うち6例に前立腺全摘術を施行, そのうち5例は摘出標本のMRIを施行し, 摘出標本の全割切片を作製し, 比較検討した.正常の前立腺は内, 外腺に分かれて摘出され, 両者の間には信号の無い境界線が存在する.さらに正常の前立腺外線はT2強調画像において, 内腺よりhigh intensityを示したが, 外腺内の癌の部分は正常の外腺よりlow intensityを示した.また, 外腺に発生した癌が内腺に浸潤していく部分に一致して内, 外腺の境界線の一部もしくは全部の消失を認めた.これらの所見はin vivoのMRIでも認められた.MRIは, 前立腺癌のlocal stagingに関し臨床的価値がある

Magnetic resonance imaging (MRI) of the prostate was accomplished in 23 patients who had prostatic cancer histologically proved by needle biopsy. Five prostates resected out of 23 patients with prostatic cancer were available for in vitro MRI. The MRI findings of the normal peripheral zone of the prostate had a high signal intensity on T2 weighted image, and the cancer nests in the peripheral zone had lower signal intensity than the normal peripheral zone. A partial or total destruction of the border line between outer zone and inner zone was observed besides than microscopic invasions. MRI also enabled us to differentiate the cancerous foci from the normal tissue at a different signal intensity of imaging in some selected cases in which the resected specimen was examined by in vitro MRI.