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Title: 泌尿器科領域における静注用クロタオンの治験
Other Titles: Clinical experiences with intravenous use of "Chlotaon" in urological diseases
Authors: 三品, 輝男  KAKEN_name
藤村, 伸  KAKEN_name
村田, 庄平  KAKEN_name
大山, 朝弘  KAKEN_name
村上, 剛  KAKEN_name
山田, 要助  KAKEN_name
保井, 明泰  KAKEN_name
大江, 宏  KAKEN_name
Author's alias: Mishina, Teruo
Fujimura, Shin
Murata, Shohei
Oyama, Choko
Murakami, Tsuyoshi
Yamada, Yosuke
Yasui, Akihiro
Ooe, Hiroshi
Keywords: Adult
Chloramphenicol/therapeutic use
Injections, Intravenous
Middle Aged
Prostatic Hyperplasia/drug therapy
Surgical Wound Infection/prevention & control
Troleandomycin/therapeutic use
Urinary Calculi/drug therapy
Urinary Tract Infections/drug therapy
Issue Date: May-1968
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 14
Issue: 5
Start page: 541
End page: 546
Abstract: "Chlotaon", each vial containing 333 mg of chloramphenicol and 167 mg oleandomycin, was administered intravenously to 28 operated patients for prophylaxis of postoperative infection and to 11 patients with urinary tract infection. The inhibition of postoperative infection was achieved in 25 out of 28 patients (89.3%). In cases of urinary tract infection, definite improvement of symptoms and urinary findings were observed in 10 out of 20 patients (50%), including 9 operative cases who had urinary tract infection preoperatively. The less effectiveness of the drug in this group of urinary tract infection might be due to the fact that a half of bacteria had resistance to these antibiotics. However, our clinical experience indicated that a better effectiveness is presented when this antibiotic is used according to the results of sensitivity test. Based on these results, it is supposed that "Chlotaon" of intravenous use is one of the excellent antibiotics in urologic practice. No noticeable side effect was encountered in all patients administered.
PubMed ID: 4178204
Appears in Collections:Vol.14 No.5

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