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タイトル: | 泌尿器腫瘍と酵素 4.Dimethylnitrosamineによる実験的腎腫瘍における Lactic Dehydrogenase,Alkaline Phosphatase,Leucine Aminopeptidase,Total Acid Phosphatase 活性およびLDH isozymesの変動について |
その他のタイトル: | Urological neoplasms and enzyme. IV. Studies on the alteration of lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, and total acid phosphatase activities and LDH isozymes in experimentally induced renal tumors with dimethylnitrosamine |
著者: | 石部, 知行 |
著者名の別形: | Ishibe, Tomoyuki |
キーワード: | Acid Phosphatase/metabolism Alkaline Phosphatase/metabolism Animals Isoenzymes Kidney Neoplasms/chemically induced/enzymology L-Lactate Dehydrogenase/metabolism Leucyl Aminopeptidase/metabolism Male Nitrosamines |
発行日: | Jun-1968 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 14 |
号: | 6 |
開始ページ: | 307 |
終了ページ: | 312 |
抄録: | In order to induce renal tumors, Wistar strain rats were given special food containing 500 ppm of dimsthylnitrosamins for 2 wesks. Renal and serum activities of lactic dehydrogenase (LDH), alkaline phosphatase (AlP), leucine aminopeptidase (LAP), total acid phosphatase (TAP) and LDH isozymes were determined successively. The results are summarized as follows. 1. Both of serum and renal LDH activities markedly increased after the 7th month of the experimental period. At the same time the LDH isozymes pattern showed increases of M type and the fraction III with a decrease of H type. 2. Both of serum and renal AQP activities slightly decreased during the latter half of the experimental period. 3. LAP activity slightly decreased in the kidney and increased in serum along with the elapse of time. 4. TAP activity showed no definite trend both in the kidney and in serum. |
URI: | http://hdl.handle.net/2433/119875 |
PubMed ID: | 5750091 |
出現コレクション: | Vol.14 No.6 |
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