尿路感染症に対するSP-125(Dicloxacillin)の使用経験

Abstract

SP-125 (each 1 capsule contains 125 mg of Dicloxacillin) was applied clinically in a daily dose of 1000 mg in 4 divided doses in various infectious conditions of the urinary tract in the field of urology and the following results were obtained. 1) Out of 25 cases of urinary tract infections treated, there were 16 cases of very effective, 7 cases of effective and 2 ineffective cases, so a rate of effectiveness was 92 %. This rate of effectiveness, howevET, was obtained in acute infections and the same effectiveness cannot be expected in chronic infections. The results in chronic prostatitis and seminal vesiculitis verify this. 2) The effect of the agent against the organisms isolated from the cases was examined. It was extremely effective against cocci but ineffective against bacilli. It was found that infection by bacilli developed during treatment and this can be considered a natural phenomenon in view of the antibacterial spectrum of the agent. Measures to prevent this must be taken. In our cases, other agents which act against bacilli are given concomitantly. 3) Side effects were not observed even in a single case.