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Title: 前立腺癌に対するDithizoneの局所注入療法について
Other Titles: Treatment of prostatic carcinoma with local injection of dithizone
Authors: 石部, 知行  KAKEN_name
福重, 満  KAKEN_name
田中, 広見  KAKEN_name
溝口, 勝  KAKEN_name
藤本, 洋治  KAKEN_name
Author's alias: Ishibe, Tomiyuki
Fukushige, Mitsuru
Tanaka, Hiromi
Mizoguchi, Masaru
Fujimoto, Yoji
Keywords: Humans
Indicators and Reagents/administration & dosage
Prostatic Hyperplasia/drug therapy
Prostatic Neoplasms/drug therapy
Issue Date: Dec-1968
Publisher: 京都大学医学部泌尿器科学教室
Journal title: 泌尿器科紀要
Volume: 14
Issue: 12
Start page: 886
End page: 895
Abstract: Thirteen cases of carcinoma and two cases of benign hyperplasia of the prostate resistant to hormone therapy were treated with dithizone (diphenylthiocarbazid) either by intraprostatic injection (10) or by oral administration (5). In 13 of 15, clinical improvement was obtained as well as diminished prostatic size. Blood chemistry suggested some hepatotoxicity even under local injection which gave obviously less side effects than general administration. This drug, therefore, can be very useful for carcinoma of the prostate non-responsive to antiandrogen treatment if carefully administered.
PubMed ID: 4180160
Appears in Collections:Vol.14 No.12

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