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dc.contributor.author大越, 正秋ja
dc.contributor.author名出, 頼男ja
dc.contributor.author川村, 猛ja
dc.contributor.author川上, 隆ja
dc.contributor.author鈴木, 恵三ja
dc.contributor.author長久保, 一朗ja
dc.contributor.alternativeOkoshi, Masakien
dc.contributor.alternativeNaide, Yorioen
dc.contributor.alternativeKawamura, Takeshien
dc.contributor.alternativeKawakami, Takashien
dc.contributor.alternativeSuzuki, Keizoen
dc.contributor.alternativeNagakubo, Ichiroen
dc.date.accessioned2010-06-02T06:19:19Z-
dc.date.available2010-06-02T06:19:19Z-
dc.date.issued1969-10-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/120053-
dc.description.abstractEvaluation of AC-PC or 6-(aminocyclohexane carboxamide) penicillanic acid has been done in the laboratory and clinically. By oral administration of single dose of 250 mg, peak blood level of 10 γ/ml was attained at 30 minutes after administration which showed rapid absorption of the drug in the alimentary tract. About 40 % of the amount taken was excreted in urine within 2 hours with peak level of 2, 000 γ/ml. Minimal inhibitory concentration of AC-PC was much higher against Gram-negative rod bacteria than that of ampicillin or carbenicillin. However, AC-PC has been effective in the treatment of primary acute infections of the urinary tract. The pathogens were mostly E. coli strains. The effectiveness of this drug in the treatment of simple urinary infections might be due to high drug level in urine which exceeds minimal inhibitory concentration against the pathogens.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher京都大学医学部泌尿器科学教室ja
dc.publisher.alternativeDepartment of Urology, Faculty of Medicine, Kyoto Univeersityen
dc.subjectCystitis/drug therapyen
dc.subjectHumansen
dc.subjectMicrobial Sensitivity Testsen
dc.subjectPenicillins/adverse effects/metabolism/therapeutic useen
dc.subjectUrethritis/drug therapyen
dc.subjectUrinary Tract Infections/drug therapyen
dc.subject.ndc494.9-
dc.title尿路感染症に対するAC-PCの応用 --基礎的および臨床的研究--ja
dc.title.alternativeStudy on AC-PC against urinary tract infection--fundamental and clinical investigationen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume15-
dc.identifier.issue10-
dc.identifier.spage744-
dc.identifier.epage747-
dc.textversionpublisher-
dc.sortkey08-
dc.address慶応義塾大学医学部泌尿器科学教室ja
dc.address.alternativeThe Department of Urology, Keio University School of Medicineen
dc.identifier.pmid5390816-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.15 No.10

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