原発性男子深部尿道腺癌の1例

Abstract

Carcinoma of the urethra is rare, and adenocarcinoma of the deep urethra is far more rare in the male. An 83-year-old man was seen with the chief complaint of dysuria and urethral bleeding. The patient had past history of gonococcal urethritis and urethral stricture. The urethrography revealed an irregular defect in the bulbomembranous urethra. Pathohistological study of the necrotic tissue in urine suggested adenocarcinoma of the urethra. The biopsy of inguinal lymph nodes disclosed metastatic adenocarcinomas bilaterally. Considering his age and heart disease, no surgical treatment was performed. A tumor dose of 4800 r radium was delivered transurethrally and 5022r Co60 was given over both inguinal region. He died of uremia and septicemia one year after his first admission. The autopsy revealed urethral adenocarcinoma invading into corpus cavernosum and metastases to the retroperitoneal and Virchow's lymph node, lungs, liver, pancreas and kidneys. In reviewing the Japanese literature, this report was the 78th case of urethral carcinomas and the 2nd case of adenocarcinomas of the deep urethra in male. The patient in this case, being 83-year-old, was the oldest reported.