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dc.contributor.author杉山, 高秀ja
dc.contributor.author郡, 健二郎ja
dc.contributor.author八竹, 直ja
dc.contributor.author栗田, 孝ja
dc.contributor.alternativeSugiyama, Takahideja
dc.contributor.alternativeKohri, Kenjiroja
dc.contributor.alternativeYachiku, Sunaoja
dc.contributor.alternativeKurita, Takashija
dc.date.accessioned2010-06-03T04:33:35Z-
dc.date.available2010-06-03T04:33:35Z-
dc.date.issued1983-08ja
dc.identifier.issn0018-1994ja
dc.identifier.urihttp://hdl.handle.net/2433/120217-
dc.description.abstract尿路性器癌の転移による骨性疼痛をきたした13例にCTを投与した.1)鎮痛効果は13例中11例(85%)にみられた.とくに前立腺癌できわめて有効であった.2)鎮痛効果発現日は8.2日で,総投与量1,000単位投与した時点で効果判定をおこなってよい.3)正常なCa値の症例では,CT投与前後における血清Ca,P,内分泌の動きに変化はなかったja
dc.description.abstractCalcitonin obtained from eels (ell-CT) was given to 14 patients who had developed bony pains due to bone metastases of malignant tumors and who did not respond to 12 various analgesics. The patients consisted of 12 males and 2 females, with a mean age of sixty-five. Eel-CT (Elcitonin) was injected intramuscularly to each patient at a dose of 40 units twice daily. Other analgesics were assessed to be ineffective at the time of CT administration and they were not given consideration in the evaluation. For the assessment of drug effect, a pain score was prepared. Eel-CT was markedly effective in 3 patients, effective in 8 patients, and ineffective in 2 patients. Eel-CT had a better effect on prostatic cancer than any other cancer. The analgesic effect was observed in the first week of drug administration at around a total dose of 1,000 units. Although the pain tended to appear at regions on which the body weight was liable to rest, the analgesic effect was seen irrespective of the side of pain. Since serum calcium, phosphate, parathyroid hormone (PTH), CT levels and bone scintigrams between pre-and post-CT administration did not differ, the analgesic mode of action of CT is not supposed to be related to inhibition of bone absorption nor bone formation. The therapeutic effect hardly suggests any direct action of CT on the tumor.ja
dc.format.mimetypeapplication/pdfja
dc.language.isojpnja
dc.publisher泌尿器科紀要刊行会ja
dc.subjectAdenocarcinoma/physiopathology/secondaryja
dc.subjectAgedja
dc.subjectAnimalsja
dc.subjectBone Neoplasms/physiopathology/secondaryja
dc.subjectCalcitonin/therapeutic useja
dc.subjectEelsja
dc.subjectFemaleja
dc.subjectFemoral Fractures/therapyja
dc.subjectHormones/therapeutic useja
dc.subjectHumansja
dc.subjectKidney Neoplasms/surgeryja
dc.subjectMaleja
dc.subjectMiddle Agedja
dc.subjectPain, Intractable/drug therapyja
dc.subject.ndc494.9ja
dc.title尿路性器癌の骨転移による骨性疼痛に対するカルシトニンの効果ja
dc.title.alternativeEffect of calcitonin on body pains caused by bone metastases of urogenital cancerja
dc.type.niitypeDepartmental Bulletin Paperja
dc.identifier.ncidAN00208315ja
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume29ja
dc.identifier.issue8ja
dc.identifier.spage953ja
dc.identifier.epage958ja
dc.textversionpublisherja
dc.sortkey14ja
dc.address近畿大学医学部泌尿器科学教室ja
dc.address.alternativeThe Department of Urology, Kinki University School of Medicineja
dc.identifier.pmid6675446ja
Appears in Collections:Vol.29 No.8

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