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Title: Basedow氏病に対する131I治療の既往にみられた副甲状腺機能亢進症の1例
Other Titles: Hyperparathyroidism after radioactive iodine therapy for Graves' disease: a case report
Authors: 川村, 寿一  KAKEN_name
鳶巣, 賢一  KAKEN_name
真田, 俊吾  KAKEN_name
岡田, 裕作  KAKEN_name
吉田, 修  KAKEN_name
南, 俊介  KAKEN_name
日野, 恵  KAKEN_name
滋野, 長平  KAKEN_name
小西, 淳二  KAKEN_name
森田, 隆司  KAKEN_name
鳥塚, 莞爾  KAKEN_name
Author's alias: Kawamura, Juichi
Tobisu, Kenichi
Sanada, Shungo
Okada, Yusaku
Yoshida, Osamu
Minami, Shunsuke
Hino, Megumi
Shigeno, Tyohei
Konishi, Junji
Morita, Rikushi
Torizuka, Kanji
Keywords: Adult
Follow-Up Studies
Graves Disease/radiotherapy
Iodine Radioisotopes/adverse effects/therapeutic use
Issue Date: Nov-1983
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 29
Issue: 11
Start page: 1513
End page: 1519
Abstract: Herein we report a 36-year-old man with hyperparathyroidism and a past history of internal irradiation to the thyroid. Twelve years previously at age 24 years he had received 8 mCi of radioactive iodine for Graves' disease. An additional dose of 4 mCi was required 3 years later. A right lower parathyroid adenoma (28 X 23 X 20 mm, 5.7 g) was found at neck exploration. Although the association of external ionizing radiation to the head and neck and the subsequent development of hyperfunctioning parathyroid glands has been described in recent years, there are only 4 cases in the literature of parathyroid surgery for hyperparathyroidism secondary to earlier treatment with radioactive iodine for Graves' disease. In a long-term follow-up of 180 patients treated with radioactive iodine for Graves' disease, neither hypercalcemia nor hypophosphatemia was found. Whether internal radiation therapy can be a causative factor in the development of hyperparathyroidism should be elucidated in future. However, it seems reasonable to suggest that patients whose hyperthyroidism has been treated with radioactive iodine should have their serum calcium levels examined at 5-year intervals.
PubMed ID: 6689566
Appears in Collections:Vol.29 No.11

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