ダウンロード数: 270
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
29_1469.pdf | 384.79 kB | Adobe PDF | 見る/開く |
タイトル: | 細胞診による膀胱腫瘍術後の評価 |
その他のタイトル: | Value of cytological examination for postoperative bladder cancer |
著者: | 川地, 義雄 |
著者名の別形: | Kawachi, Yoshio |
キーワード: | Cytodiagnosis Follow-Up Studies Humans Neoplasm Staging Urinary Bladder Neoplasms/diagnosis/pathology/surgery |
発行日: | Nov-1983 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 29 |
号: | 11 |
開始ページ: | 1469 |
終了ページ: | 1474 |
抄録: | 膀胱腫瘍術後の20例を対象に, 細胞診を主体とした術後評価をおこなった.初回の治療としておもにTURと術後ADM膀注療法を施行した.術後細胞診陽性例は13例で, 多発性, 最大径1 cm以上, high gradeおよび浸潤性発育の腫瘍に陽性例が多く見られた.Grade 3とStage pT2の症例は全例が術後細胞診陽性で, うち約半数に残存腫瘍組織を確認した.術後細胞診陽性, 生検組織診療性例は, 術後の抗癌剤膀注療法で細胞診の陰性化が見られた.検体の比較では, 膀胱洗滌液が新鮮尿に比べて高い細胞診陽性率を示したが, 新鮮尿にも意義を認めた In this preliminary report the usefulness of cytological examinations is emphasized in any follow-up for bladder cancer after surgery. In this study, 20 cases of bladder cancer, 3 of which were initially treated by TUC , 16 by TUR, and one by segmental resection, were followed-up regularly by consecutive cytologies, cystoscopy, and biopsies. Anti-cancer drugs were instilled intravesically after the initial surgery in 16 cases. Cytological examinations one month after surgery gave negative results in 7 cases and positive results in 13 cases; cancer cells were confirmed by means of surgical specimens or biopsy in 6 of the latter cases. Positive cytology was documented in 7/9 cases of multiple tumors, in 10/13 cases of tumors larger than 1 cm in diameter, in 7/7 cases of grade 3 tumors, and in 9/9 cases of tumors more advanced than pTa. Positive cytology and negative biopsy were converted to negative in 7 cases by vesical instillation therapy, even in 4 cases with grade 3 tumors and in 2 cases with pT2 . In 6 cases with histologically proved cancer, urine cytology was positive or suspicious in 37.5% (positive in 25.0%) and vesical washing cytology was positive or suspicious in 71.1% (positive in 44.4%). In 7 cases with positive cytology and negative biopsy, urine cytology was positive or suspicious in 20.6% (positive in 7.7%) and vesical washing cytology was positive or suspicious in 70.8% (positive in 43.6%). The above results reveal that in diagnosing cancer in the bladder, washing-fluid cytology is superior to conventional urinary cytology.(ABSTRACT TRUNCATED AT 250 WORDS) |
URI: | http://hdl.handle.net/2433/120286 |
PubMed ID: | 6677099 |
出現コレクション: | Vol.29 No.11 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。