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タイトル: | 男性不妊に関する研究 --男性不妊患者精漿における乳酸脱水素酵素Isozymeについて-- |
その他のタイトル: | Studies on male infertility. Lactic dehydrogenase isozymes of the seminal plasma in infertile men |
著者: | 斉藤, 博 |
著者名の別形: | Saito, Hiroshi |
キーワード: | Humans Infertility, Male/enzymology Isoenzymes L-Lactate Dehydrogenase/analysis Male Semen/enzymology Spermatozoa/enzymology Staining and Labeling |
発行日: | May-1970 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 16 |
号: | 5 |
開始ページ: | 222 |
終了ページ: | 230 |
抄録: | 1. LDH-isozymes of the seminal plasma was investigated in 171 infertile men. Polyacrylamide gel disc electrophoresis was used to obtain zymograms. In 63 cases, concentration of each isozyme fraction was determined with microdensitometer. 2. Out of 34 azoospermic cases, 26 seminal plasmas showed only three bands of LDHisozymes. They consisted of postvasectomy 3, germ cell apJasia 10, spermatogenic arrest 8, and hypospermatogenesis 5. 3. In 106 oligozoospermic cases, number of LDH-isozyme bands was correlated with sperm concentration. 4. No correlation was found between sperm motility rate and number of LDH-isozyme bands. 5. Densitometry of LDH-isozyme bands demonstrated constant ratio of them without regard to histological findings of the testes. On the other hand, oligozoospermic and normozoospermic cases showed high concentration of LDH3 in the three-bands group or of LDH5 in the five-bands group in good correlation with sperm concentration. |
URI: | http://hdl.handle.net/2433/121120 |
PubMed ID: | 4195043 |
出現コレクション: | Vol.16 No.5 |
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