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Title: 非特異性尿路感染症の細菌学的検索(第2報) (付: Gentamicinの尿路感染症への応用)
Other Titles: A bacteriologic study on non-specific urinary tract infection and clinical evaluation of gentamicin
Authors: 杉村, 克治  KAKEN_name
中山, 宗文  KAKEN_name
中島, 純子  KAKEN_name
吉田, キヨ  KAKEN_name
Author's alias: Sugimura, Katsuharu
Nakayama, Munefumi
Yoshida, Kiyo
Keywords: Adult
Aged
Chronic Disease
Drug Resistance, Microbial
Female
Gentamicins/adverse effects/therapeutic use
Humans
Male
Middle Aged
Urinary Tract Infections/drug therapy/microbiology
Issue Date: Jun-1970
Publisher: 京都大学医学部泌尿器科学教室
Journal title: 泌尿器科紀要
Volume: 16
Issue: 6
Start page: 287
End page: 297
Abstract: 1. Culture and sensitivity test in non-specific urinary tract infection during four years of 1966 to 1969 were summarized and compared with those of preceding four years. 2. As causative organisms, bacilli increased and cocci decreased to only 10 % of them. Of bacilli, E. coli occupied 50 %, being followed by Proteus, Pseudomonas and Klebsiella. Increase of Klebsiella was conspicuous. Of cocci, Staphylococcus was a leading organism whose incidence was same as that of Pseudomonas. 3. Sensitivity test showed excellence of gentamicin and kanamycin for bacilli as well as that of novobiocin, aminobenzyl penicillin and cephaloridine for cocci. For E. coli, gentamicin, kanamycin, cephaloridine and nalidixic acid showed good sensitivity. For Proteus, gentamicin, kanamycin and nalidixic acid were highly sensitive. Pseudomonas showed resistance against most of the drugs except gentamicin. For Klebsiella, gentamicin, kanamycin and cephaloridine were excellent; and for Staphylococcus, cephaloridine, aminobenzyl penicillin and kanamycin were so. lt can be said that kanamycin was still highly sensitive against various microorganisms except Pseudomonas. Gentamicin showed the best sensitivity against all kinds of the organism. On the other hand, aminobenzyl penicillin found resistant organisms more than expected. Evaluation of the sulfa drugs varied depending upon the quantity of inoculated organisms. When the inoculated amount was small, the sensitivity was high. 4. Sixteen chronic urinary tract infections were treated with gentamicin and all the cases responded well. No side effects were proved except for slightly decreased PSP value.
URI: http://hdl.handle.net/2433/121130
PubMed ID: 5465253
Appears in Collections:Vol.16 No.6

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