膀胱腫瘍に対する超高圧放射線治療法の経験

Abstract

Since August of 1966, we have treated bladder tumor by external irradiation with the 6MeV linear accelerator. The effect of this treatment, side reaction, and remote result were here investigated. Most of the cases tolerated well the irradiation and could receive the sufficient therapeutic dose. One to twelve months observation of 52 cases showed disappearance of tumor of the bladder in 23 cases (44.2%). Even in grade III and IV group, 43.9% got free of tumor. Shrinkage of tumor was in progress 3 to 4 months after irradiation in the low grade group and 5 months in the high grade group. The remote result was never inferior to that of total cystectomy. From the results of super-high voltage external irradiation and that of operative treatment, our principle of treatment of the bladder tumor was established as follows. 1) Single and low grade tumor should be treated by open or transurethral surgery. The close follow-up study is important. 2) In aged patients or poor risk cases, in which surgery is not recommended, the external irradiation shoud be tried first. 5) The multiple or high grade tumor should be also treated first by the irradiation followed by six months observation. Depending on the local finding, the operative treatment or re-irradiation should be tried.