Conraxin D使用によるDrip Infusion Pyelographyの検討

Abstract

Drip infusion pyelography (DIP) was carried out with 200 ml of Conraxin D (a 32.45 per cent methylglucamine iodamide solution) in 72 cases including 13 cases of renal insufficiency, and its diagnostic availability and safety were studied. As for the diagnostic availability, a good urogram was obtained in about 60 per cent of the cases, when total renal function was normal, and in 75 per cent of the cases in which the BUN was 25 to 40 mg/100 ml and the serum creatinine value was 2.0 to 3.5 mg/100 ml, so that retrograde pyelography could be omitted in these cases. As for the safety, side effects were encountered in 37.5 per cent of the cases, though they were not serious. The effect on the cardiovascular system was examined by means of changes in the blood pressure and pulse, but almost no effect was observed. It showed no marked effect on the renal function, serum electrolytes and liver functions. This was true even in all the cases of renal insufficiency. From these facts, Conraxin D is believed to be a contrast medium which can safely be used for DIP. Other favorable aspects of Conraxin D are that it does not need to be diluted before DIP, and rapid drip infusion can easily be carried out being finished within 10 minutes, even if a relatively narrow needle of 19 gauge is used, because of its low viscosity as 1.72 cps at 25℃, so it is suitable for DIP. Conraxin D is, therefore, quite suitable for DIP.