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Title: Gentamicinの局所療法
Other Titles: The studies on the treatment of urinary tract or wound-fistula infections after the urological operations with local infusion of gentamicin
Authors: 古沢, 太郎  KAKEN_name
藤村, 伸  KAKEN_name
大山, 朝弘  KAKEN_name
大江, 宏  KAKEN_name
Author's alias: FURUSAWA, Taro
OHYAMA, Chyoko
OHE, Hiroshi
Keywords: Adolescent
Gentamicins/administration & dosage
Infusions, Parenteral
Kidney Pelvis
Middle Aged
Postoperative Complications/drug therapy
Surgical Wound Infection/drug therapy
Urinary Bladder
Urinary Catheterization
Urinary Fistula
Urinary Tract Infections/drug therapy
Urogenital System/surgery
Issue Date: Jun-1971
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 17
Issue: 6
Start page: 420
End page: 428
Abstract: We tried the local infusion therapy with gentamicin t o 31 patients (total sites : 37) with urinary tract or surgical wound infection, which developed after urological operation and failed to respond to many other antibiotics. 1. The infusion can be divided into three groups as follows : 1) In 16 cases, gentamicin was infused into the renal pel v is through nephrostomy catheter or retragrade ureteral catheter (splint catheter). 2) In 8 cases, gentamicin was infused int o the bladder through suprapubic cystostomy catheter or transurethral indwelling catheter. 3) In 13 cases, gentamicin was infused d i rectly or through drain into the wound fistula. 2. Gentamicin injectable, original solution or solution diluted to 3 or 4 times with sterile distilled water, was infused into the locals 1 or 2 times daily for more than 3 days. 3. Before the treatment with gentamicin, microorganisms such as Proteus or Pseudomonas were isolated from urine or purulent discharge. The topical treatments with gent a micin were all successful except one case (pyelonephritis) which improved later on by intramuscular administration. Though there were some patients with renal or hepatic impairment before the treatment with gentamicin, no adverse reaction was observed for a course of gentamicin therapy.
PubMed ID: 5105499
Appears in Collections:Vol.17 No.6

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