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dc.contributor.author | 大山, 朝弘 | ja |
dc.contributor.alternative | Ohyama, Choko | en |
dc.date.accessioned | 2010-07-06T08:33:11Z | - |
dc.date.available | 2010-07-06T08:33:11Z | - |
dc.date.issued | 1972-06 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/121390 | - |
dc.description.abstract | In 38 mongrel dogs with an obstructed kidney produced by 10, 20, 30, 40, 50 and 60-day unilateral ligation, evaluation was made of kidney function just after release of obstruction and 2 months thereafter by both renal clearance and furosemide diuresis tests. The furosemide diuresis meant here refers to urinary output per min during a 15-min period from 5 min to 20 min after the intravenous injection of 10mg furosemide. 1) In the group with 10-day ligation CPAH, CSTS and furosemide diuresis were found decreased to 3.9 %, 2.4 % and 19.0 %, respectively, on the average, of corresponding values for the unaffected kidney just after removal of obstruction and then increased to 54.0 %, 56.9 % and 115.0 % respectively 2 months thereafter. 2) In the group with 20-day ligation CPAH, CSTS and furosemide diuresis were found de-creased to 1.9 %, 0.5 and 3.2 %, respectively, on the average, of corresponding values for the unaffected kidney just after removal of obstruction and then increased to 59.0 %, 67.1 % and 118.1 % respectively 2 months thereafter. 3) In the group with 30-day ligation CPAH, CSTS and furosemide diuresis were found decreased to 0.3 %, 0.4 % and 4.3 %, respectively, on the average, of corresponding values for the unaffected kidney just after removal of obstruction and then increased to 38.8 %, 37.9 % and 55.2 % respectively 2 months thereafter. 4) In the group with 40-day ligation CPAH, CSTS and furosemide diuresis were found decreased to 0.1 %, 0.2 % and 3.3 %, respectively, on the average, of corresponding values for the unaffected kidney just after removal of obstruction and then increased to 12.2 %, 14.9 % and 22.7 % respectively 2 months thereafter. 5) In the group with 50-day ligation CPAH, CSTS and furosemide diuresis were found decreased to 0.3 %, 0.3 % and 0.3 %, respectively, on the average, of corresponding values for the unaffected kidney just after removal of obstruction and then increased to 4.3 %, 3.8 % and 5.9 % respectively 2 months thereafter. 6) In the group with 60-day ligation CPAH, CSTS and furosemide diuresis were found de creased to 0.2%, 0.2 % and 0.0 %, respectively, on the average, of corresponding values for the unaffected kidney just after removal of obstruction and then increased to 3.5 %, 2.6 % and 5.2 % respectively 2 months thereafter. 7) A nonfunctioning kidney was demonstrated both by renal clearance and furosemide diuresis tests just after removal of obstruction in groups receiving ligation for 40 days or longer as well as 2 months after the release in the groups with 50 days or longer ligation. 8) Furosemide acted on the non-obstructed kidney in such a way to increase excretion fraction of water (EFH2O) by 13.3 % just after removal of obstruction and 8.8 % 2 months thereafter, while it caused increase of EFH2O by 20.0 % and 14.9 % respectively on the obstructed kidney. 9) The diuretic effect of furosemide was thus unexpectedly greater on the affected than on the unaffected kidney and, in this respect, was somewhat dissimilar , to GFR, but there was a positive correlation noted between these parameters. 10) Based on these results and available literature, discussion was made on functional recovery of the obstructed kidney. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 京都大学医学部泌尿器科学教室 | ja |
dc.publisher.alternative | Department of Urology, Faculty of Medicine, Kyoto Univeersity | en |
dc.subject.ndc | 494.9 | - |
dc.title | 慢性閉塞腎の機能とその回復性に関する実験的研究 - フロセミド利尿効果による慢性閉塞腎の機能測定 | ja |
dc.title.alternative | EXPERIMENTAL STUDIES ON KIDNEY FUNCTION AND ITS RECOVERY AFTER COMPLETE CHRONIC UNILATERAL URETERAL OBSTRUCTION - EVALUATION OF FUNCTION OF CHRONICALLY OBSTRUCTED KIDNEY BY MEANS OF FUROSEMIDE-INDUCED DIURESIS - | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 18 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 373 | - |
dc.identifier.epage | 390 | - |
dc.textversion | publisher | - |
dc.sortkey | 02 | - |
dc.address | 京都府立医科大学泌尿器科学教室 | ja |
dc.address.alternative | The Department of Urology, Kyoto Prefectural University of Medicine | en |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.18 No.6 |
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