膀胱腫瘍の臨床統計 - 第2報 治療方法と遠隔成績との関係(統計法への考察)

Abstract

Statistical analysis was performed on tumors of the urinary bladder seen in the Department of Urology of Nagoya City University Hospital during 20 years from January of 1948 to December of 1967. In this report, relationship between treatments and 5-year survival of 116 cases was studied. 1) Five-year survival rates of untreated cases and patients treated with TUF or TUR, simple resection of the tumor, partial cystectomy and simple total cystectomy were calculated. a) Twenty-four untreated cases (average life span; 60.7 years) Crude survival rate : 22.7% Observed survival rate: 28.0% Relative survival rate : 36.6% b) Thirty cases with TUF or TUR (average life span; 60.0 years) Crude survival rate : 66.7% Observed survival rate: 73.8% Relative survival rate : 88.5% c) Eighteen cases with simple resection of the tumor (average life span; 58.2 years) Crude survival rate : 56. 3% Observed survival rate: 63.8% Relative survival rate : 74.9% d) Twenty-four cases with partial cystectomy (average life span; 62.1 years) Crude survival rate 36.8% Observed survival rate: 46.8% Relative survival rate : 63.1% e) Thirteen cases with , simple total cystectomy (average life span; 58.2 years) Crude survival rate 23.1% Observed survival rate: 23. 1% Relative survival rate : 27.0% f) All (116) cases (average life span; 63. a years) Crude survival rate : 45.7% Observed survival rate: 64.6% Relative survival rate : 80.0% 2) We compared several methods of survival analyzation and concluded that the best method was computation of relative survival rate. 3) Standard errors of 5•year relative survival rates were calculated and statistical reliability was estimated. a) Five-year relative survival rate of patients with TUF or TUR was significantly higher than that of patients with simple total cystectomy (p<0.5%). b) Five-year relative survival rate of patients with TUF or TUR was significantly higher than that of untreated cases (p<5%). c) Five-year relative survival rate of patients with simple resection of the tumor was significantly higher than that of patients with simple total cystectomy (p<2.5%). d) No significant difference was observed between other groups.