HFSHキットおよびHLHキットによるLH-RH負荷後の男子性腺機能不全患者におけるFSH,LHの測定

Abstract

HFSH and HLH radioimmunoassay kits were evaluated and the plasma FSH and LH in men with gonadal dysfunction were measured after LH-RH stimulations. The measurement procedure with the kit is simple and it offers no problem. As to the precision, in FSH quality of the results was not always better than those obtained by other methods, while in LH they were well comparable with the latter. From this fact, it can be concluded that this method is adaptable enough for the routine determination of the hormones. The values of plasma FSH and LH reached the highest in 20-60 minutes after LH-RH stimulations. Except in one case of hypogonadism, the response was rather poor in FSH, while in LH, the response increased remarkably. Correlation between the degree of increase of LH or FSH and the physiological condition of seminal fluid was not recognized specially because of a few number of cases. We consider that LH-RH stimulation test is indispensable for examining the function of the hypothalamo-pituitary-gonadal system.