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タイトル: | Klinefelter症候群にかんする臨床的研究 - 1.Klinefelter症候群におけるLH-RH試験 |
その他のタイトル: | CLINICAL STUDIES ON KLINEFELTER'S SYNDROME - 1. LH-RH TEST IN KLINEFELTER’S SYNDROME |
著者: | 小松, 洋輔 友吉, 唯夫 永山, 洋一 |
著者名の別形: | Komatsu, Yosuke Tomoyoshi, Tadao Nagayama, Yoichi |
発行日: | Sep-1973 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 19 |
号: | 9 |
開始ページ: | 789 |
終了ページ: | 794 |
抄録: | 100µg of synthetic LH-RH was intravenously administered to seven cases of Klinefelter's syndrome with karyotype of 47, XXY and the plasma LH and FSH were determined to know their pituitary response. The following results were obtained. 1. The maximum response level of plasma LH (134.2±89.4 mIU/ml) was observed at 20 minutes. The maximum net increase and factorial increase were 96.5±79.9mIU/ml and 4.0± 2.6 respectively. The LH level remained significantly higher even at 60 minutes. 2. The plasma FSH showed increase of 1.2 to 1.4 times of the pretest level, the maximum net increase being 58.0±21.6 mIU/ml. There was however, no significant difference between them. The pituitary gonadotropin-producing cells of Klinefelter's syndrome were capable to response to synthetic LH-RH and possessed reserved ability to excrete excessive amount of LH and FSH. |
URI: | http://hdl.handle.net/2433/121564 |
出現コレクション: | Vol.19 No.9 |
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