尿路感染症に対するThiophenicol glycinate(Neomyson G)の使用経験

Abstract

1) Thiophenicol glycinate (Neomyson G) was administered intravenously 1 to 4 grams per day to the patients with urinary tract infection for two to seven days. The following results were obtained. Out of 13 outpatients, 9 showed excellent response, 2 fairly good, and 2 no response. Therapeutic effect was noted in 69.296. 2) Out of 16 inpatients, nobody showed excellent response, two fairly good and 12 no response. Therapeutic effect was therefore evaluated as 12.5 %. 3) Sensitivity test with disc method was carried out on 73 strains isolated from 29 patients treated with Neomyson G. 72.2 % of outpatients and 10.9 % of inpatients showed sensitivity. 4) Neomyson G was particularly effective against E. coli. 5) Neomyson G was effective in the treatment of simple cystitis but not so good in that of complicated cystitis. 6) As to side effects, 2 stomatitis, 1 numb hand and 1 leukopenia were noted but they disappeared quickly after discontinuing the drug. Neomyson G can be recommended as the first choice drug in the treatment of urinary tract infection at the outpatient clinic, and it is also useful for the selected cases of complicated infection.