泌尿器科領域の疼痛に対するpentazocine内服錠の鎮痛効果とそれに伴う鎮静効果の検討

Abstract

Pentazocine was administered orally at the dose of 25 mg once or twice a day to sixteen inpatients with post-operative pain and seven inpatients with non-operative urogenital pain. If pentazocine was not effective at the dose of 25 mg (the first administration), 25 mg was added after 30 minutes from the first administration (the second administration). 1. Analgesic effect: The effective rate after the first administration was 39.1 %. However, if the second administration was inclusive, it resulted in 47.8 %. 2. Sedative effect: Sedative eflect appeared in 39.1 % of the first administration cases. The second administration increased the efficacy. 3. Side effect Side effect was observed in three cases of the first administration as in sweating, dizziness and vomiting. 4. Our clinical studies suggest that the dose of 50 mg (once of 50 mg or twice of 25 mg) is better in effect than that of 25 mg (once of 25 mg).