前立腺肥大症に対する19-nor-hydroxy-progesterone caproate(SH-582)の臨床効果

Abstract

During the period from August 1968 to May 1970 we treated with SH-582 a total of 45 in- or out-patients in the Urological Departments of Kobe University Hospital or of the other related hospitals who were diagnosed as having prostatic hypertrophy by palpation, urethrography, cystoscopy and biopsy. As a rule SH-582 was intramuscularly administered in one dose of 300 mg every week. Improvement in difficult urination, reduction in residual urine volume, changes in size of the adenoma were collectively taken into consideration for estimation of the therapeutic efficacy. The therapeutic effect was very good in 17 patients and good in 19 patients, while treatment produced no effect in 9 patients. The efficacy rate was 80.0%, which may be considered almost satisfactory. There were no side-effects in any patient.