男性不妊症の臨床的観察 付.Mesteroloneの治療経験

Abstract

A clinical observation was made on male outpatients who visited the Department of Urology, Niigata University Hospital during 2 years, 1971 and 1972 with chief complaints of infertility. A follow-up study was done in all of them in order to make sure pregnancy incidence. Four hundreds and three men visited the anthors' clinic with complaints of infertility, which corresponded to 9.9% of a total number of outpatients and 14.9% of total male outpatients. Age distribution ranged from 22-year-old to 61-year-old with an average of 30.7 years. Most of them visited the clinic for consultation within 5 years after their marriage, 43.6% being within 3 years. 15.7% of their spouses revealed to have some gynecological disorders. Of 349 patients who had semen analysis done, 43.0% showed normospermia, 11.2% hypospermia, 9.8% oligospermia, 8.0% oligo-asthenospermia, 3.4% asthenospermia, 1.4% teratospermia and 23.2% azoospermia. The follow-up study showed that pregnancy was reported in 19.0% of all the patients and in 41.5% of the patients who gave certified answers. Patients in 1971 gave a significantly higher rate of pregnancy than those of 1972. Pregnancy incidence in the normospermic group did not significantly differ from that of the hypospermic group. In the treated group (mesterolone, PMS and others) rates of pregnancy and improvement in seminal findings were 11.6% and 35.2%, respectively, while pregnancy rate in the untreated group (normospermic cases excluded) was 10.7%.