膀胱刺激症状に対するFlavoxate錠の臨床的効果について - 二重盲検法による検討 -

Abstract

Clinical effect of ftavoxate for nervous pollakisuria and irritable bladder was investigated by a double blind method with butylscopolamine bromide as a standard drug. The following results were obtained. 1. One hundred and one case (51 of the favoxate group, and 50 of the standard drug group) were submitted for analysis. No pre-test difference was noted between two groups as to age, sex, diagnosis, history, previous treatment, symptoms, severity and complications. 2. Therapeutic effect on each symptom was analyzed statistically. Flavoxate was significantly superior to standard drug for frequent urination, urinary urgency and unpleasant feeling after urination. There was no difference in the effect on amount of residual urine. Urinary incontinence was slightly better treated with ftavoxate. 3. As an overall evaluation, ftavoxate showed marked therapeutic effect with significant superiority to the standard drug. 4. Side effect was seen in 18.8% of the ftavoxate group and 25.0% of the standard drug group. In only one case of each group, however, the medication was discontinued.