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Title: 共存によるurokinase,thio-TEPAの薬剤安定性の検討
Other Titles: CROSS EFFECTS OF UROKINASE AND THIO-TEPA ON THEIR STABILITIES
Authors: 久住, 治男  KAKEN_name
三崎, 俊光  KAKEN_name
Author's alias: Hisazumi, Haruo
Misaki, Toshimitsu
Issue Date: Aug-1975
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 21
Issue: 8
Start page: 743
End page: 747
Abstract: In order to obtain a more adequate therapeutic effect of thio-TEPA for the prevention of recurrence of bladder cancer, the authors have used the combined vesical instillation of urokinase. Herein, cross effects of urokinase and thio-TEPA on their stabilities have been studied in vitro. Urokinase and thio-TEPA showed no deteriorating effect each other under some mixing conditions resembling closely the practical administration. Macrogol 400 which is contained in Tespamin®, a stabilizer for thio-TEPA, increased urokinase activity in a fibrin plate assay system.
URI: http://hdl.handle.net/2433/121864
Appears in Collections:Vol.21 No.8

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